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Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation

Histone modifications have been implicated in stem cell maintenance and differentiation. We have analyzed genome-wide changes in gene expression and histone modifications during differentiation of multipotent human primary hematopoietic stem/progenitor cells (HSCs/HPCs) into erythrocyte precursors....

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Detalhes bibliográficos
Main Authors: Cui, Kairong, Zang, Chongzhi, Roh, Tae-Young, Schones, Dustin E., Childs, Richard W., Peng, Weiqun, Zhao, Keji
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785912/
https://ncbi.nlm.nih.gov/pubmed/19128795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.11.011
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