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Evolutionary Plasticity and Innovations in Complex Metabolic Reaction Networks
Genome-scale metabolic networks are highly robust to the elimination of enzyme-coding genes. Their structure can evolve rapidly through mutations that eliminate such genes and through horizontal gene transfer that adds new enzyme-coding genes. Using flux balance analysis we study a vast space of met...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785887/ https://ncbi.nlm.nih.gov/pubmed/20019795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000613 |
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