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Characterization of Influenza Virus Variants with Different Sizes of the Non-structural (NS) Genes and Their Potential as a Live Influenza Vaccine in Poultry

From a stock of A/turkey/Oregon/71-delNS1 (H7N3) virus, which has a 10 nucleotide deletion in the coding region of the NS1 gene, we found that several variants with different sizes of NS genes could be produced by passaging the virus in 10- and 14-day-old embryonating chicken eggs (ECE), but not in...

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Detalhes bibliográficos
Main Authors: Wang, L., Suarez, D. L., Pantin-Jackwood, M., Mibayashi, M., García-Sastre, A., Saif, Y. M., Lee, C-W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785844/
https://ncbi.nlm.nih.gov/pubmed/18539366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.05.001
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