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DNA-AP sites generation by Etoposide in whole blood cells

BACKGROUND: Etoposide is currently one of the most commonly used antitumor drugs. The mechanisms of action proposed for its antitumor activity are based mainly on its interaction with topoisomerase II. Etoposide effects in transformed cells have been described previously. The aim of the present stud...

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Detalhes bibliográficos
Main Authors: Rojas, Emilio, Mussali, Patricia, Tovar, Efrain, Valverde, Mahara
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785836/
https://ncbi.nlm.nih.gov/pubmed/19917085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-398
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