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Condensins Regulate Meiotic DNA Break Distribution, thus Crossover Frequency, by Controlling Chromosome Structure

Meiotic crossover (CO) recombination facilitates evolution and accurate chromosome segregation. CO distribution is tightly regulated: homolog pairs receive at least one CO, CO spacing is nonrandom, and COs occur preferentially in short genomic intervals called hotspots. We show that CO number and di...

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Hlavní autoři: Mets, David G., Meyer, Barbara J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785808/
https://ncbi.nlm.nih.gov/pubmed/19781752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.035
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