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Dynamin 2 orchestrates the global actomyosin cytoskeleton for epithelial maintenance and apical constriction

The mechanisms controlling cell shape changes within epithelial monolayers for tissue formation and reorganization remain unclear. Here, we investigate the role of dynamin, a large GTPase, in epithelial morphogenesis. Depletion of dynamin 2 (Dyn2), the only dynamin in epithelial cells, prevents esta...

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Detalhes bibliográficos
Main Authors: Chua, Jennifer, Rikhy, Richa, Lippincott-Schwartz, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785724/
https://ncbi.nlm.nih.gov/pubmed/19948954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909812106
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