Structural Basis for the Kexin-like Serine Protease from Aeromonas sobria as Sepsis-causing Factor

The anaerobic bacterium Aeromonas sobria is known to cause potentially lethal septic shock. We recently proposed that A. sobria serine protease (ASP) is a sepsis-related factor that induces vascular leakage, reductions in blood pressure via kinin release, and clotting via activation of prothrombin....

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Main Authors: Kobayashi, Hidetomo, Utsunomiya, Hiroko, Yamanaka, Hiroyasu, Sei, Yoshihisa, Katunuma, Nobuhiko, Okamoto, Keinosuke, Tsuge, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785694/
https://ncbi.nlm.nih.gov/pubmed/19654332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006114
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