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Key Residues in Mycobacterium tuberculosis Protein Kinase G Play a Role in Regulating Kinase Activity and Survival in the Host

Protein kinase G (PknG) in Mycobacterium tuberculosis has been shown to modulate phagosome-lysosome fusion. The protein has three distinct domains, an N-terminal Trx domain, a kinase domain, and a C-terminal TPR domain. The present study extensively analyzes the roles of these domains in regulating...

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Detalhes bibliográficos
Main Authors: Tiwari, Divya, Singh, Rajnish Kumar, Goswami, Kasturi, Verma, Sunil Kumar, Prakash, Balaji, Nandicoori, Vinay Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785676/
https://ncbi.nlm.nih.gov/pubmed/19638631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036095
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