Antigen Specificity of γδ T Cells Depends Primarily on the Flanking Sequences of CDR3δ

The structural basis that determines the specificity of γδ T cell receptor (TCR) recognition remains undefined. Our previous data show that the complementary determining region of human TCRδ (CDR3δ) is critical to ligand binding. Here we used linear and configurational approaches to examine the role...

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Autors principals: Xi, Xueyan, Guo, Yang, Chen, Hui, Xu, Chunping, Zhang, Huiyuan, Hu, Hongbo, Cui, Lianxian, Ba, Denian, He, Wei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785674/
https://ncbi.nlm.nih.gov/pubmed/19666468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011684
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