Toll-like Receptors of the Ascidian Ciona intestinalis: PROTOTYPES WITH HYBRID FUNCTIONALITIES OF VERTEBRATE TOLL-LIKE RECEPTORS

Key transmembrane proteins in the innate immune system, Toll-like receptors (TLRs), have been suggested to occur in the genome of non-mammalian organisms including invertebrates. However, authentic invertebrate TLRs have been neither structurally nor functionally investigated. In this paper, we orig...

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Bibliographische Detailangaben
Hauptverfasser: Sasaki, Naoko, Ogasawara, Michio, Sekiguchi, Toshio, Kusumoto, Shoichi, Satake, Honoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Mechanisms of Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785661/
https://ncbi.nlm.nih.gov/pubmed/19651780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032433
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