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Elimination of the CDP-ethanolamine Pathway Disrupts Hepatic Lipid Homeostasis
Phosphoethanolamine cytidylyltransferase (ECT) catalyzes the rate-controlling step in a major pathway for the synthesis of phosphatidylethanolamine (PtdEtn). Hepatocyte-specific deletion of the ECT gene in mice resulted in normal appearing animals without overt signs of liver injury or inflammation....
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785637/ https://ncbi.nlm.nih.gov/pubmed/19666474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031336 |
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