SufA of the Opportunistic Pathogen Finegoldia magna Modulates Actions of the Antibacterial Chemokine MIG/CXCL9, Promoting Bacterial Survival during Epithelial Inflammation

The anaerobic bacterium Finegoldia magna is part of the human commensal microbiota, but is also an important opportunistic pathogen. This bacterium expresses a subtilisin-like serine proteinase, SufA, which partially degrade the antibacterial chemokine MIG/CXCL9. Here, we show that MIG/CXCL9 is prod...

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Main Authors: Karlsson, Christofer, Eliasson, Mette, Olin, Anders I., Mörgelin, Matthias, Karlsson, Anna, Malmsten, Martin, Egesten, Arne, Frick, Inga-Maria
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Enzyme Catalysis and Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785583/
https://ncbi.nlm.nih.gov/pubmed/19628464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025957
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