Inhibition of Adaptive Immune Responses Leads to a Fatal Clinical Outcome in SIV-Infected Pigtailed Macaques but Not Vervet African Green Monkeys

African green monkeys (AGM) and other natural hosts for simian immunodeficiency virus (SIV) do not develop an AIDS-like disease following SIV infection. To evaluate differences in the role of SIV-specific adaptive immune responses between natural and nonnatural hosts, we used SIV(agmVer90) to infect...

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Main Authors: Schmitz, Jörn E., Zahn, Roland C., Brown, Charles R., Rett, Melisa D., Li, Ming, Tang, Haili, Pryputniewicz, Sarah, Byrum, Russell A., Kaur, Amitinder, Montefiori, David C., Allan, Jonathan S., Goldstein, Simoy, Hirsch, Vanessa M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785481/
https://ncbi.nlm.nih.gov/pubmed/20011508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000691
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