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Inflammasome-dependent Caspase-1 Activation in Cervical Epithelial Cells Stimulates Growth of the Intracellular Pathogen Chlamydia trachomatis

Inflammasomes have been extensively characterized in monocytes and macrophages, but not in epithelial cells, which are the preferred host cells for many pathogens. Here we show that cervical epithelial cells express a functional inflammasome. Infection of the cells by Chlamydia trachomatis leads to...

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Autors principals: Abdul-Sater, Ali A., Koo, Evonne, Häcker, Georg, Ojcius, David M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785367/
https://ncbi.nlm.nih.gov/pubmed/19648107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026823
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