Chargement en cours...

ADP-ribosylation of human defensin HNP-1 results in the replacement of the modified arginine with the noncoded amino acid ornithine

Defensins (e.g., human neutrophil peptides, or HNPs) contribute to innate immunity through diverse actions, including microbial killing; high concentrations are present in the lung in response to inflammation. Arginines are critical for HNP activity, which is decreased by their replacement with orni...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Stevens, Linda A., Levine, Rodney L., Gochuico, Bernadette R., Moss, Joel
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785246/
https://ncbi.nlm.nih.gov/pubmed/19897717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910633106
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!