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Autotaxin/Lysophospholipase D-mediated Lysophosphatidic Acid Signaling Is Required to Form Distinctive Large Lysosomes in the Visceral Endoderm Cells of the Mouse Yolk Sac

Autotaxin, a lysophospholipase D encoded by the Enpp2 gene, is an exoenzyme that produces lysophosphatidic acid in the extracellular space. Lysophosphatidic acid acts on specific G protein-coupled receptors, thereby regulating cell growth, migration, and survival. Previous studies have revealed that...

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Detalhes bibliográficos
Main Authors: Koike, Seiichi, Keino-Masu, Kazuko, Ohto, Tatsuyuki, Sugiyama, Fumihiro, Takahashi, Satoru, Masu, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785199/
https://ncbi.nlm.nih.gov/pubmed/19808661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.012716
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