Fast Diffusion of Very Long Chain Saturated Fatty Acids across a Bilayer Membrane and Their Rapid Extraction by Cyclodextrins: IMPLICATIONS FOR ADRENOLEUKODYSTROPHY

Abnormalities in the transport of saturated very long chain fatty acids (VLCFA; >C18:0) contribute to their toxic levels in peroxisomal disorders of fatty acid metabolism, such as adrenoleukodystrophy and adrenomyeloneuropathy. We previously showed that VLCFA desorb much slower than normal dietar...

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Bibliographic Details
Main Authors: Pillai, Biju K., Jasuja, Ravi, Simard, Jeffrey R., Hamilton, James A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Membrane Transport, Structure, Function, and Biogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785172/
https://ncbi.nlm.nih.gov/pubmed/19801636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043737
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