The Interferon Consensus Sequence Binding Protein (ICSBP/IRF8) Activates Transcription of the FANCF Gene during Myeloid Differentiation

The interferon consensus sequence binding protein (ICSBP) is an interferon regulatory transcription factor with leukemia-suppressor activity. ICSBP regulates genes that are involved in phagocyte function, proliferation, and apoptosis. In murine models ICSBP deficiency results in a myeloproliferative...

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Bibliographic Details
Main Authors: Saberwal, Gurveen, Horvath, Elizabeth, Hu, Liping, Zhu, Chunliu, Hjort, Elizabeth, Eklund, Elizabeth A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Transcription, Chromatin, and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785167/
https://ncbi.nlm.nih.gov/pubmed/19801548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.010231
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