Interaction between the SifA Virulence Factor and Its Host Target SKIP Is Essential for Salmonella Pathogenesis

SifA is a Salmonella effector that is translocated into infected cells by the pathogenicity island 2-encoded type 3 secretion system. SifA is a critical virulence factor. Previous studies demonstrated that, upon translocation, SifA binds the pleckstrin homology motif of the eukaryotic host protein S...

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Bibliografiske detaljer
Main Authors: Diacovich, Lautaro, Dumont, Audrey, Lafitte, Daniel, Soprano, Elodie, Guilhon, Aude-Agnès, Bignon, Christophe, Gorvel, Jean-Pierre, Bourne, Yves, Méresse, Stéphane
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Membrane Transport, Structure, Function, and Biogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785157/
https://ncbi.nlm.nih.gov/pubmed/19801640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.034975
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