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N-Glycosylation Regulates Fibroblast Growth Factor Receptor/EGL-15 Activity in Caenorhabditis elegans in Vivo

The regulation of cell function by fibroblast growth factors (FGFs) classically occurs through a dual receptor system of a tyrosine kinase receptor (FGFR) and a heparan sulfate proteoglycan co-receptor. Mutations in some consensus N-glycosylation sites in human FGFR result in skeletal disorders and...

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Detalhes bibliográficos
Main Authors: Polanska, Urszula M., Duchesne, Laurence, Harries, Janet C., Fernig, David G., Kinnunen, Tarja K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785143/
https://ncbi.nlm.nih.gov/pubmed/19801543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.058925
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