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Transfection of HepG2 cells with hGSTA4 provides protection against 4-hydroxynonenal-mediated oxidative injury

4-hydroxynonenal (4-HNE) is a mutagenic α,β-unsaturated aldehyde produced during oxidative injury that is conjugated by several glutathione S-transferase (GST) isoforms. The alpha class human GSTA4-4 enzyme (hGSTA4-4) has a particularly high catalytic efficiency toward 4-HNE conjugation. However, hG...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Gallagher, Evan P., Huisden, Christiaan M., Gardner, James L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785086/
https://ncbi.nlm.nih.gov/pubmed/17553661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2007.04.004
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