Trans-Synaptic Transfer of Wnt Signals Through Release of Evi/Wntless Vesicles and Trafficking of Postsynaptic Frizzled-2 Receptors

Wnts play pivotal roles during development and in the mature nervous system. However, the mechanism by which Wnts traffic between cells has remained elusive. Here we demonstrate a novel mechanism of Wnt transmission through release of exosome-like vesicles containing the Wnt-binding protein Evenness...

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Bibliographic Details
Main Authors: Korkut, Ceren, Ataman, Bulent, Ramachandran, Preethi, Ashley, James, Barria, Romina, Gherbesi, Norberto, Budnik, Vivian
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785045/
https://ncbi.nlm.nih.gov/pubmed/19837038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.051
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