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Radiotherapy in Conjunction with 7-Hydroxystaurosporine: A Multimodal Approach with Tumor pO(2) as a Potential Marker of Therapeutic Response
Checkpoint inhibitors potentially could be used to enhance cell killing by DNA-targeted therapeutic modalities such as radiotherapy. UCN-01 (7-hydroxystaurosporine) inhibits S and G(2) checkpoint arrest in the cells of various malignant cell lines and has been investigated in combination with chemot...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785035/ https://ncbi.nlm.nih.gov/pubmed/19883227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1781.1 |
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