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Radiotherapy in Conjunction with 7-Hydroxystaurosporine: A Multimodal Approach with Tumor pO(2) as a Potential Marker of Therapeutic Response

Checkpoint inhibitors potentially could be used to enhance cell killing by DNA-targeted therapeutic modalities such as radiotherapy. UCN-01 (7-hydroxystaurosporine) inhibits S and G(2) checkpoint arrest in the cells of various malignant cell lines and has been investigated in combination with chemot...

詳細記述

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書誌詳細
主要な著者: Khan, Nadeem, Mupparaju, Sriram P., Hou, Huagang, Lariviere, Jean P., Demidenko, Eugene, Swartz, Harold M., Eastman, Alan
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785035/
https://ncbi.nlm.nih.gov/pubmed/19883227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1781.1
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