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Broadly Reactive Monoclonal Antibodies to Multiple HIV-1 Subtype and SIVcpz Envelope Glycoproteins

The extraordinarily high level of genetic variation of HIV-1 env genes poses a challenge to obtain antibodies that cross-react with multiple subtype Env glycoproteins. To determine if cross-reactive monoclonal antibodies (mAbs) to highly conserved epitopes in HIV-1 envelope glycoproteins can be indu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gao, Feng, Scearce, Richard M., Alam, S Munir, Hora, Bhavna, Xia, Shimao, Hohm, Julie E., Parks, Robert J., Ogburn, Damon F., Tomaras, Georgia D., Park, Emily, Lomas, Woodrow E., Maino, Vernon C., Fiscus, Susan A., Cohen, Myron S., Moody, M Anthony, Hahn, Beatrice H., Korber, Bette T., Liao, Hua-xin, Haynes, Barton F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785033/
https://ncbi.nlm.nih.gov/pubmed/19744690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.07.041
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