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AICAR Preconditioning Prevents Postischemic Leukocyte Rolling and Adhesion: Role of K(ATP) Channels and Heme Oxygenase

OBJECTIVE: We previously demonstrated that pharmacologic activation of AMP-activated protein kinase (AMPK) with 5-aminoimidazole-4-carboxamide 1-β-D-ribofuranoside (AICAR) 24 hours prior to (AICAR preconditioning; AICAR-PC) ischemia/reperfusion (I/R) prevents postischemic leukocyte-endothelial cell...

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Detalhes bibliográficos
Main Authors: GASKIN, F. SPENCER, KAMADA, KAZUHIRO, YUSOF, MOZOW, DURANTE, WILLIAM, GROSS, GARRETT, KORTHUIS, RONALD J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784925/
https://ncbi.nlm.nih.gov/pubmed/19152177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10739680802355897
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