Activation of Retinoic Acid Receptors by Dihydroretinoids

Vitamin A-derived metabolites act as ligands for nuclear receptors controlling the expression of a number of genes. Stereospecific saturation of the C(13)-C(14) double bond of all-trans-retinol by the enzyme, retinol saturase (RetSat), leads to the production of (R)-all-trans-13,14-dihydroretinol. I...

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Main Authors: Moise, Alexander R., Alvarez, Susana, Domínguez, Marta, Alvarez, Rosana, Golczak, Marcin, Lobo, Glenn P., von Lintig, Johannes, de Lera, Angel R., Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784734/
https://ncbi.nlm.nih.gov/pubmed/19770350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.060038
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