Heme Oxygenase-2 Deletion Causes Endothelial Cell Activation Marked by Oxidative Stress, Inflammation, and Angiogenesis

In previous studies, we have shown that heme oxygenase (HO)-2 null [HO-2(−/−)] mice exhibit a faulty response to injury; chronic inflammation and massive neovascularization replaced resolution of inflammation and tissue repair. Endothelial cells play an active and essential role in the control of in...

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Detalhes bibliográficos
Main Authors: Bellner, Lars, Martinelli, Lucia, Halilovic, Adna, Patil, Kiran, Puri, Nitin, Dunn, Michael W., Regan, Raymond F., Schwartzman, Michal Laniado
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Cellular and Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784722/
https://ncbi.nlm.nih.gov/pubmed/19773531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.158352
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