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Heme Oxygenase-2 Deletion Causes Endothelial Cell Activation Marked by Oxidative Stress, Inflammation, and Angiogenesis
In previous studies, we have shown that heme oxygenase (HO)-2 null [HO-2(−/−)] mice exhibit a faulty response to injury; chronic inflammation and massive neovascularization replaced resolution of inflammation and tissue repair. Endothelial cells play an active and essential role in the control of in...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784722/ https://ncbi.nlm.nih.gov/pubmed/19773531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.158352 |
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