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Regulatory T cell (Treg) Subsets Return in Patients with Refractory Lupus Following Stem Cell Transplantation and TGF-β producing CD8+ Treg Cells (CD8(TGF-β) Treg) are Associated with Immunologic Remission of Lupus
Compared to conventional drug therapy, autologous hematopoietic stem cell transplantation (HSCT) can induce very long-term remission in refractory lupus patients. Herein, we show that in post-transplant patients, both CD4+CD25(high)FoxP3+, and an unusual CD8+FoxP3+ Treg subset return to levels seen...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784684/ https://ncbi.nlm.nih.gov/pubmed/19841178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901773 |
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