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Reversible, Temperature-Dependent Supramolecular Assembly of Aquaporin-4 Orthogonal Arrays in Live Cell Membranes

The shorter “M23” isoform of the glial cell water channel aquaporin-4 (AQP4) assembles into orthogonal arrays of particles (OAPs) in cell plasma membranes, whereas the full-length “M1” isoform does not. N-terminal residues are responsible for OAP formation by AQP4-M23 and for blocking of OAP formati...

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Autors principals: Crane, Jonathan M., Verkman, A.S.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784574/
https://ncbi.nlm.nih.gov/pubmed/19948131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.017
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