Reversible Phosphorylation Subserves Robust Circadian Rhythms by Creating a Switch in Inactivating the Positive Element

Reversible phosphorylation of proteins is ubiquitous in circadian systems, but the role it plays in generating rhythmicity is not completely understood. A common mechanism for most circadian rhythms involves a negative feedback loop between the positive and negative elements. Here, we built a minima...

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Bibliographic Details
Main Authors: Cheng, Zhang, Liu, Feng, Zhang, Xiao-Peng, Wang, Wei
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2009
Subjects:
Biophysical Systems and Multicellular Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784573/
https://ncbi.nlm.nih.gov/pubmed/19948115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.008
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