Oral high dose ascorbic acid treatment for one year in young CMT1A patients: a randomised, double-blind, placebo-controlled phase II trial

BACKGROUND: High dose oral ascorbic acid substantially improved myelination and locomotor function in a Charcot-Marie-Tooth type 1A mouse model. A phase II study was warranted to investigate whether high dose ascorbic acid also has such a substantial effect on myelination in Charcot-Marie-Tooth type...

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Autori principali: Verhamme, Camiel, de Haan, Rob J, Vermeulen, Marinus, Baas, Frank, de Visser, Marianne, van Schaik, Ivo N
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784478/
https://ncbi.nlm.nih.gov/pubmed/19909499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-7-70
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