A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy

BACKGROUND: The chemopreventive effects of dietary phytochemicals on malignant tumors have been studied extensively because of a relative lack of toxicity. To achieve desirable effects, however, treatment with a single agent mostly requires high doses. Therefore, studies on effective combinations of...

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Detalhes bibliográficos
Main Authors: Nakamura, Yoshitaka, Yogosawa, Shingo, Izutani, Yasuyuki, Watanabe, Hirotsuna, Otsuji, Eigo, Sakai, Tosiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784428/
https://ncbi.nlm.nih.gov/pubmed/19909554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-100
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