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Quercetin Prevents LPS-Induced High-Mobility Group Box 1 Release and Proinflammatory Function

The pathogenesis of sepsis is mediated in part by the pathogen-associated molecular pattern molecule bacterial endotoxin, which stimulates macrophages to sequentially release early (e.g., TNF-α, IL-1β) and late (e.g., high-mobility group box [HMGB] 1 protein) proinflammatory mediators. The recent di...

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Detalhes bibliográficos
Main Authors: Tang, Daolin, Kang, Rui, Xiao, Weimin, Zhang, Huali, Lotze, Michael T., Wang, Haichao, Xiao, Xianzhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784404/
https://ncbi.nlm.nih.gov/pubmed/19265175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0119OC
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