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Design, synthesis, and testing of difluoroboron derivatized curcumins as near infrared probes for in vivo detection of amyloid-β deposits

Amyloid-β (Aβ) deposits have been identified as key players in the progression of Alzheimer’s disease (AD). Recent evidence indicates that the deposits probably precede and induce the neuronal atrophy. Therefore, methods that enable monitoring the pathology before clinical symptoms are observed woul...

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Bibliografiske detaljer
Main Authors: Ran, Chongzhao, Xu, Xiaoyin, Raymond, Scott B., Ferrara, Brian J., Neal, Krista, Bacskai, Brian J., Medarova, Zdravka, Moore, Anna
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784241/
https://ncbi.nlm.nih.gov/pubmed/19807070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9047043
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