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CYP450 4A Inhibition Attenuates O(2) Induced Arteriolar Constriction in Chronic but not Acute Goldblatt Hypertension

We explored the role of 20-hydroxy-5Z, 8Z, 11Z, 14Z-eicosatetraenoic acid (20-HETE) in oxygen-induced vasoconstriction in a normal renin form of hypertension [the 1 kidney-1 clip Goldblatt hypertensive rat (1K1C)] and a high renin form of hypertension [the 2 kidney-1 clip Goldblatt hypertensive rat...

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Detalhes bibliográficos
Main Authors: Kunert, Mary Pat, Friesma, Jill, Falck, John R., Lombard, Julian H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784231/
https://ncbi.nlm.nih.gov/pubmed/19761780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2009.09.002
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