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Requirement for the basic helix-loop-helix transcription factor Dec2 in initial T(H)2 lineage commitment
How naïve CD4(+) T cells commit to the T helper type 2 (T(H)2) lineage is poorly understood. Here we show that the basic helix-loop-helix transcription factor Dec2 is selectively expressed in T(H)2 cells. CD4(+) T cells from Dec2-deficient mice exhibits defective T(H)2 differentiation in vitro and i...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784129/ https://ncbi.nlm.nih.gov/pubmed/19881507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1821 |
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