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Blend uniformity analysis using stream sampling and near infrared spectroscopy

A near infrared spectroscopic method was developed to determine drug content in a 20% (wt/wt) ibuprofen and spray-dried hydous lactose blend. A blending profile was obtained after blending for 0.5, 1, 3, 5, 10, and 20 minutes. Stream sampling was used to collect about 20 blend samples at each of the...

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Bibliografiske detaljer
Main Authors: Popo, Manuel, Romero-Torres, Saly, Conde, Carlos, Romañach, Rodolfo J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784053/
https://ncbi.nlm.nih.gov/pubmed/12916939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF02830622
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