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Overproduction of acyloxyacyl hydrolase by macrophages and dendritic cells prevents prolonged reactions to bacterial lipopolysaccharide in vivo

Whereas recognition of LPS by the MD-2—TLR4 receptor complex is important for triggering protective inflammatory responses in animals, terminating many of these responses requires LPS inactivation by a host lipase, acyloxyacyl hydrolase (AOAH). To test if endogenously-produced recombinant AOAH can m...

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Bibliografiske detaljer
Main Authors: Ojogun, Noredia, Kuang, Tang-Yong, Shao, Baomei, Greaves, David R., Munford, Robert S., Varley, Alan W.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783937/
https://ncbi.nlm.nih.gov/pubmed/19860560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/646616
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