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The Spontaneously Hypertensive Rat model of ADHD – the importance of selecting the appropriate reference strain

Although several molecular and genetic manipulations may produce hyperactive animals, hyperactivity alone is insufficient for the animal to qualify as a model of ADHD. Based on a wider range of criteria — behavioral, genetic and neurobiological — the spontaneously hypertensive rat (SHR) obtained fro...

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Detalhes bibliográficos
Main Authors: Sagvolden, Terje, Johansen, Espen Borgå, Wøien, Grete, Walaas, S. Ivar, Storm-Mathisen, Jon, Bergersen, Linda Hildegard, Hvalby, Øivind, Jensen, Vidar, Aase, Heidi, Russell, Vivienne A., Killeen, Peter R., DasBanerjee, Tania, Middleton, Frank A, Faraone, Stephen V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783904/
https://ncbi.nlm.nih.gov/pubmed/19698722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.08.004
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