A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding

DNA methylation is an epigenetic mark essential for mammalian development, genomic stability, and imprinting. DNA methylation patterns are established and maintained by three DNA methyltransferases: DNMT1, DNMT3A, and DNMT3B. Interestingly, all three DNMTs make use of alternative splicing. DNMT3B ha...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Gopalakrishnan, Suhasni, Van Emburgh, Beth O., Shan, Jixiu, Su, Zhen, Fields, C. Robert, Vieweg, Johannes, Hamazaki, Takashi, Schwartz, Philip H., Terada, Naohiro, Robertson, Keith D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783805/
https://ncbi.nlm.nih.gov/pubmed/19825994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0018
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы