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CRL4s: the CUL4-RING E3 ubiquitin ligases
The evolutionarily conserved cullin family proteins can assemble as many as 400 distinct E3 ubiquitin ligase complexes that regulate diverse cellular pathways. CUL4, one of three founding cullins conserved from yeast to humans, uses a large β-propeller protein, DDB1, as a linker to interact with a s...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783741/ https://ncbi.nlm.nih.gov/pubmed/19818632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2009.07.002 |
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