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A novel secreted osteoclastogenic factor of activated T cells (SOFAT) induces osteoclast formation in a RANKL-independent manner

OBJECTIVE: Chronic T cell activation is central to the etiology of rheumatoid arthritis (RA) an inflammatory autoimmune disease that leads to severe focal bone erosions and generalized systemic osteoporosis. We previously reported novel cytokine-like activities in media from activated T cells that p...

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Main Authors: Rifas, Leonard, Weitzmann, M. Neale
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783420/
https://ncbi.nlm.nih.gov/pubmed/19877052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24877
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