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Effects of the 5 Alpha-Reductase Inhibitor Dutasteride on Gene Expression in Prostate Cancer Xenografts

BACKGROUND: In the prostate, androgens play a crucial role in normal and cancerous growth; hence the androgenic pathway has become a target of therapeutic intervention. Dutasteride is a 5 alpha-reductase (5AR) inhibitor currently being evaluated both for chemoprevention and treatment of prostate can...

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Autores principales: Schmidt, Lucy J., Regan, Kevin M., Anderson, S. Keith, Sun, Zhifu, Ballman, Karla V., Tindall, Donald J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783419/
https://ncbi.nlm.nih.gov/pubmed/19676081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21022
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