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Plasma and brain concentrations of oral therapeutic doses of methylphenidate and their impact on brain monoamine content in mice

Methylphenidate is a frequently prescribed stimulant for the treatment of attention deficit hyperactivity disorder (ADHD). An important assumption in the animal models that have been employed to study methylphenidate’s effects on the brain and behavior is that bioavailability of methylphenidate in t...

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Autors principals: Balcioglu, Aygul, Ren, Jia-Qian, McCarthy, Deirdre, Spencer, Thomas J., Biederman, Joseph, Bhide, Pradeep G.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783341/
https://ncbi.nlm.nih.gov/pubmed/19631228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.07.025
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