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Inhibition of RANK Expression and Osteoclastogenesis by TLRs and IFN-γ in Human Osteoclast Precursors

TLRs have been implicated in promoting osteoclast-mediated bone resorption associated with inflammatory conditions. TLRs also activate homeostatic mechanisms that suppress osteoclastogenesis and can limit the extent of pathologic bone erosion associated with infection and inflammation. We investigat...

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Detalhes bibliográficos
Main Authors: Ji, Jong-Dae, Park-Min, Kyung-Hyun, Shen, Zenxin, Fajardo, Roberto J., Goldring, Steven R., McHugh, Kevin P., Ivashkiv, Lionel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783334/
https://ncbi.nlm.nih.gov/pubmed/19890054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900072
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