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LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphology
Most epilepsy genes encode ion channels, but the LGI1 gene responsible for Autosomal Dominant Partial Epilepsy with Auditory Features produces a secreted protein. LGI1 is suggested to regulate PSD-95 via ADAM22. However, no unbiased screen of LGI1 action has been conducted. Here, we searched for bra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783222/ https://ncbi.nlm.nih.gov/pubmed/19796686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2009.09.008 |
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