Novel Epigeneitc Mechanisms that Control Pluripotency and Quiescence of Adult Bone Marrow-Derived Oct4(+) Very Small Embryonic Like Stem Cells

Recently, we identified in adult tissues a population of Oct4(+)SSEA-1(+)Sca-1(+)lin(-)CD45(-) very small embryonic-like stem cells (VSELs). First, to address recent controversies on Oct4 expression in cells isolated from adult organs we show here an evidence that Oct4 promoter in bone marrow (BM)-d...

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Main Authors: Shin, Dong-Myung, Zuba-Surma, Ewa K., Wu, Wan, Ratajczak, Janina, Wysoczynski, Marcin, Ratajczak, Mariusz Z., Kucia, Magda
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783188/
https://ncbi.nlm.nih.gov/pubmed/19641521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.153
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