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Inactivation of cystathionine β-synthase with peroxynitrite
Cystathionine β-synthase (CBS) is a homocysteine metabolizing enzyme that contains pyridoxal phosphate (PLP) and a six-coordinate heme cofactor of unknown function. CBS was inactivated by peroxynitrite, the product of nitric oxide and superoxide radicals. The IC(50) was ~150 μM for 5 μM ferric CBS....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783175/ https://ncbi.nlm.nih.gov/pubmed/19733148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.08.022 |
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