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Self-guanylylation of birnavirus VP1 does not require an intact polymerase activity site

Protein-priming is an important mechanism that many viruses use to initiate genomic DNA or RNA synthesis. Birnaviruses are the only double-stranded (ds) RNA viruses that use protein priming. The viral-encoded VP1 of birnavirus functions as both a polymerase and a protein primer, and is able to under...

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Detalhes bibliográficos
Main Authors: Pan, Junhua, Lin, Li, Tao, Yizhi Jane
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783171/
https://ncbi.nlm.nih.gov/pubmed/19801157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.09.004
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