A model invalidation-based approach for elucidating biological signalling pathways, applied to the chemotaxis pathway in R. sphaeroides

BACKGROUND: Developing methods for understanding the connectivity of signalling pathways is a major challenge in biological research. For this purpose, mathematical models are routinely developed based on experimental observations, which also allow the prediction of the system behaviour under differ...

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Autori principali: Roberts, Mark AJ, August, Elias, Hamadeh, Abdullah, Maini, Philip K, McSharry, Patrick E, Armitage, Judith P, Papachristodoulou, Antonis
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783038/
https://ncbi.nlm.nih.gov/pubmed/19878602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-105
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